Before agar, microbiologists had experimented with other foodstuffs as microbial media. They turned to substances rich in the starches, proteins, sugars, fats, and minerals that organisms need for growth, testing with broths, bread, potatoes, polenta, egg whites, coagulated blood serums, and gelatine. However, none worked particularly well: all were easily broken down by heat and microbial enzymes, and their surface, once colonized, became mushy and unsuitable for isolating microbes.
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Ubisoft told VGC, which first reported on Hocking's exit, that development on Hexe will continue. Jean Guedson, one of three new leaders of the Assassin's Creed franchise, will take over as the upcoming title's new creative director. Guedson had the same role for Assassin's Creed Origins and Black Flag, two of the franchise's most well-received entries.